About Me

Sepehr Rahmani

Experience & Accomplishments

My scientific background combines biochemistry, molecular pathology, bioinformatics, and software engineering. Throughout my academic training and professional career, I have developed a strong interest in translating computational approaches into practical solutions for molecular diagnostics and precision medicine.

Currently, I work at the University Hospital Zurich, where I develop bioinformatics pipelines, software applications, and databases that support molecular diagnostics and clinical research. Alongside my technical work, I contribute to the coordination of clinical workflows for next-generation sequencing (NGS) diagnostics, combining computational expertise with clinical operations.

Outside of work, I enjoy playing football and have been involved in the sport in various roles, including as a referee. I value teamwork, continuous learning, and tackling complex challenges through collaboration. Get in contact with me to receive more information!

Work & Publications

2026

  • Prevalence and characteristics of NTRK fusions in 25,946 patients with non-small cell lung cancer — Co-First author
    Lung Cancer 218, 109514 (2026).
    DOI: https://doi.org/10.1016/j.lungcan.2026.109514
  • Co-alterations associated with resistance to EGFR inhibitors in advanced EGFR-positive NSCLC: insights from the precision oncology program in two large international real-world cohorts
    npj Precision Oncology (2026).
    DOI: https://doi.org/10.1038/s41698-026-01617-5

2025

  • Comprehensive genomic profiling for homologous recombination deficiency guides PARP inhibitor therapy recommendations in ovarian cancer — Co-author
    Pathology & Oncology Research 31 (2025).
    DOI: https://doi.org/10.3389/pore.2025.1612266
  • Nodal gamma-delta T-cell lymphoma: expression of TFH-markers causing diagnostic difficulties in a newly described entity — 3rd author
    Virchows Archiv (2025).
    DOI: https://doi.org/10.1007/s00428-025-04268-2
  • Precision Oncology Program (POP), an observational study using real-world data and imaging mass cytometry to explore decision support for the Molecular Tumor Board: study protocol
    BMJ Open 15(3), e096591 (2025).
    DOI: https://doi.org/10.1136/bmjopen-2024-096591
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Recommendations

The Weber Group at the Institute of Molecular Cancer Research (IMCR) and the University hospital Zurich, Switzerland
The Ahmadian Group at the Heinrich-Heine-University Dusseldorf, Germany
MTP_pic
The Molecular Tumor Profiling (MTP) group under the supervision of Dr. Martin Zoche at the University Hospital Zurich, Switzerland

ABOUT Me

I graduated in biochemistry with a focus in bioinformatics and I have the ambition to learn new things everyday and gain more experience! Please contact me if you are interested in further information about my research and experiences.